Identification of Cryptosporidium parvum Dihydrofolate Reductase Inhibitors by Complementation in Saccharomyces cerevisiae

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Published inAntimicrobial Agents and Chemotherapy Vol. 44; no. 4; pp. 1019 - 1028
Main Authors BROPHY, V. H, VASQUEZ, J, NELSON, R. G, FORNEY, J. R, ROSOWSKY, A, SIBLEY, C. H
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.04.2000
Subjects
Alleles
Animals
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Cryptosporidium parvum
Cryptosporidium parvum - drug effects
Cryptosporidium parvum - enzymology
Cryptosporidium parvum - genetics
Folic Acid Antagonists
Folic Acid Antagonists - pharmacology
Genetic Complementation Test
Humans
Medical sciences
Pharmacology. Drug treatments
Plasmids - genetics
Plasmodium falciparum - enzymology
Saccharomyces cerevisiae
Saccharomyces cerevisiae - drug effects
Saccharomyces cerevisiae - enzymology
Saccharomyces cerevisiae - genetics
Susceptibility
Tetrahydrofolate Dehydrogenase
Tetrahydrofolate Dehydrogenase - genetics
Tetrahydrofolate Dehydrogenase - metabolism
Toxoplasma - enzymology
Protozoa
Apicomplexa
Yeast
Enzyme
Enzyme inhibitor
Gene expression
In vitro
Fungi
Antifolate
Plasmid
Promoter
Antibiotic
Cryptosporidium parvum
Mutagenesis
Genetics
Ascomycetes
Complementation
Oxidoreductases
Dihydrofolate reductase
Recombinant protein
Antibacterial agent
Saccharomyces cerevisiae
Thallophyta
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Corresponding author. Mailing address: Department of Genetics, Box 357360, University of Washington, Seattle, WA 98195-7360. Phone: (206) 685-9378. Fax: (206) 543-0754. E-mail: sibley@genetics.washington.edu.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.44.4.1019-1028.2000