Therapeutic Efficacy of Liposomal Rifabutin in a Mycobacterium avium Model of Infection

• Published in: Antimicrobial Agents and Chemotherapy Vol. 44; no. 9; pp. 2424 - 2430
• Main Authors: GASPAR, M. M, NEVES, S, PORTAELS, F, PEDROSA, J, SILVA, M. T, CRUZ, M. E. M
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.09.2000
• Subjects: Animals; Antibacterial agents; Antibiotic Prophylaxis; Antibiotics, Antitubercular; Antibiotics, Antitubercular - administration & dosage; Antibiotics, Antitubercular - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Chemistry, Pharmaceutical; Cholesterol - chemistry; Disease Models, Animal; Drug Administration Schedule; Drug Carriers; Drug Delivery Systems; Experimental Therapeutics; General pharmacology; Liposomes - chemistry; Male; Medical sciences; Mice; Mice, Inbred BALB C; Mycobacterium avium; Mycobacterium avium - drug effects; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Rifabutin; Rifabutin - administration & dosage; Rifabutin - therapeutic use; Tuberculosis; Tuberculosis - drug therapy; Tuberculosis - prevention & control; Particle size; Intravenous administration; Drug carrier; Mycobacterial infection; Dose activity relation; Multiple dose; Prevention; Formulation; Bacteria; Phosphatidylserine; Pharmaceutical technology; Rodentia; Liposome; Mycobacterium avium; Long term; Biological activity; Infection; Rifabutin; Vertebrata; Antibiotic; Chemotherapy; Mammalia; Treatment; Mouse; Mycobacteriales; Animal; Bacteriosis; Mycobacteriaceae; Dosage form; Phosphatidylcholine; Actinomycetes; Antibacterial agent
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.44.9.2424-2430.2000

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