Penicillin Pharmacodynamics in Four Experimental Pneumococcal Infection Models

• Published in: Antimicrobial Agents and Chemotherapy Vol. 45; no. 4; pp. 1078 - 1085
• Main Authors: ERLENDSDOTTIR, Helga, KNUDSEN, Jenny Dahl, ODENHOLT, Inga, CARS, Otto, ESPERSEN, Frank, FRIMODT-MØLLER, Niels, FUURSTED, Kurt, KRISTINSSON, Karl G, GUDMUNDSSON, Sigurdur
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.04.2001
• Subjects: Animals; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Diffusion Chambers, Culture; Drug Administration Schedule; Experimental Therapeutics; Half-Life; Lung - microbiology; Medical sciences; Mice; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Penicillins - administration & dosage; Penicillins - pharmacokinetics; Penicillins - therapeutic use; Peritoneum - microbiology; Peritonitis - drug therapy; Peritonitis - metabolism; Pharmacology. Drug treatments; Pneumococcal Infections; Pneumococcal Infections - drug therapy; Pneumococcal Infections - metabolism; Pneumonia, Pneumococcal - drug therapy; Pneumonia, Pneumococcal - metabolism; Rabbits; Serum Bactericidal Test; Streptococcus pneumoniae; Thigh - microbiology; Animal model; Pharmacokinetic pharmacodynamic relationship; Pneumonia; Lung; Rabbit; Respiratory system; Blood; Blood plasma; Penicillin derivatives; Penicillin; Bacteria; Micrococcales; Subcutaneous administration; Chest wall; Peritonitis; Lung disease; Respiratory disease; Thigh; β-Lactams; Rodentia; Lagomorpha; Biological activity; Streptococcus pneumoniae; Infection; Resistance; Streptococcaceae; Vertebrata; Chemotherapy; Mammalia; Sensitivity resistance; Treatment; Mouse; Abdominal disease; Animal; Bacteriosis; Antibacterial agent; Pharmacokinetics; Comparative study; Peritoneum
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.45.4.1078-1085.2001

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