VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice

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Published inAntimicrobial Agents and Chemotherapy Vol. 50; no. 3; pp. 984 - 993
Main Authors ENTERLEIN, Sven, WARFIELD, Kelly L, SWENSON, Dana L, STEIN, David A, SMITH, Jeffery L, GAMBLE, C. Scott, KROEKER, Andrew D, IVERSEN, Patrick L, BAVARI, Sina, MÜHLBERGER, Elke
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.03.2006
Subjects
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral Agents
Biological and medical sciences
Cercopithecus aethiops
Dose-Response Relationship, Drug
Ebola virus
Ebolavirus
Ebolavirus - drug effects
Ebolavirus - genetics
Female
Filovirus
Hemorrhagic Fever, Ebola
Hemorrhagic Fever, Ebola - immunology
Hemorrhagic Fever, Ebola - mortality
Hemorrhagic Fever, Ebola - prevention & control
Kinetics
Marburg virus
Medical sciences
Mice
Mice, Inbred C57BL
Morpholines
Morpholines - pharmacology
Peptides - chemistry
Pharmacology. Drug treatments
Reverse Transcriptase Polymerase Chain Reaction
RNA, Viral - genetics
Vero Cells
Viral Proteins
Viral Proteins - pharmacology
Viral Regulatory and Accessory Proteins
Virus Replication - drug effects
Virus Replication - genetics
Mortality
Rodentia
Virus
Amplification
Infection
Prevention
Ebola virus
Mononegavirales
Vertebrata
Mammalia
Mouse
Filoviridae
Animal
Inhibitor
Filovirus
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Corresponding author. Mailing address for Elke Mühlberger: Department of Virology, Philipps-University Marburg, Hans-Meerwein-Str. 3, 35043 Marburg, Germany. Phone: 49 6421 28-65357. Fax: 49 6421 28-68962. E-mail: muehlber@staff.uni-marburg.de. Mailing address for Sina Bavari: U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702-5011. Phone: (301) 619-4246. Fax: (301) 619-2348. E-mail: sina.bavari@us.army.mil.
Both authors contributed equally to this work.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.50.3.984-993.2006