Ampicillin Enhances Daptomycin- and Cationic Host Defense Peptide-Mediated Killing of Ampicillin- and Vancomycin-Resistant Enterococcus faecium

• Published in: Antimicrobial Agents and Chemotherapy Vol. 56; no. 2; pp. 838 - 844
• Main Authors: SAKOULAS, George, BAYER, Arnold S, POGLIANO, Joseph, TSUJI, Brian T, YANG, Soo-Jin, MISHRA, Nagendra N, NIZET, Victor, YEAMAN, Michael R, MOISE, Pamela A
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.02.2012
• Subjects: Ampicillin; Ampicillin - administration & dosage; Ampicillin - pharmacology; Ampicillin - therapeutic use; Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobial Cationic Peptides; Antimicrobial Cationic Peptides - chemistry; Antimicrobial Cationic Peptides - pharmacology; Antimicrobial Cationic Peptides - therapeutic use; Bacteremia - microbiology; beta-Lactams - administration & dosage; beta-Lactams - pharmacology; beta-Lactams - therapeutic use; Biological and medical sciences; Daptomycin; Daptomycin - pharmacology; Daptomycin - therapeutic use; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Endocarditis, Bacterial - microbiology; Enterococcus faecium; Enterococcus faecium - drug effects; Enterococcus faecium - growth & development; Enterococcus faecium - isolation & purification; Humans; Mechanisms of Action: Physiological Effects; Medical sciences; Microbial Sensitivity Tests; Models, Biological; Pharmacology. Drug treatments; Treatment Outcome; Vancomycin - pharmacology; Vancomycin Resistance; Penicillin derivatives; Streptococcaceae; Enterococcus faecium; Lactic acid bacteria; Antibiotic; Ampicillin; β-Lactams; Daptomycin; Bacteria; Micrococcales; Antibacterial agent; Lipopeptide
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.05551-11

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