Systems Biology

The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reac...

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Bibliographic Details
Main Authors Rigoutsos, Isidore, Stephanopoulos, Gregory
Format eBook
LanguageEnglish
Published Oxford Oxford University Press 2006
Oxford University Press, Incorporated
Edition1
Subjects
Bioinformatics
Computational biology
Genetics & Genomics
Genetics (non-medical)
Genetics and Genomics
Genomics
Life Sciences
MATHEMATICS
Numerical analysis
Numerical and Computational Mathematics
Probability & Statistics
Probability & statistics
Probability and Statistics
SCIENCE
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ISBN0195300807
9780195300802
9780195300819
0195300815
DOI10.1093/oso/9780195300802.001.0001

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Summary:The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reach. The processing and interpretation of these new vast quantities of interconnected data call for sophisticated mathematical models and computational methods. Systems biology meets this need by combining genomic knowledge with theoretical, experimental and computational approaches from a number of traditional scientific disciplines to create a mechanistic explanation of cellular systems and processes. Systems Biology I: Genomics and Systems Biology II: Networks, Models, and Applications offer a much-needed study of genomic principles and their associated networks and models. Written for a wide audience, each volume presents a timely compendium of essential information that is necessary for a comprehensive study of the subject. The chapters in the two volumes reflect the hierarchical nature of systems biology. Chapter authors-world-recognized experts in their fields-provide authoritative discussions on a wide range of topics along this hierarchy. Volume I explores issues pertaining to genomics that range from prebiotic chemistry to noncoding RNAs. Volume II covers an equally wide spectrum, from mass spectrometry to embryonic stem cells. The two volumes are meant to provide a reliable reference for students and researchers alike.
ISBN:0195300807
9780195300802
9780195300819
0195300815
DOI:10.1093/oso/9780195300802.001.0001