Pharmacodynamic Profile of Ertapenem against Klebsiella pneumoniae and Escherichia coli in a Murine Thigh Model

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Published inAntimicrobial Agents and Chemotherapy Vol. 49; no. 1; pp. 276 - 280
Main Authors MAGLIO, Dana, BANEVICIUS, Mary Anne, SUTHERLAND, Christina, BABALOLA, Chinedum, NIGHTINGALE, Charles H, NICOLAU, David P
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.01.2005
Subjects
Animals
Anti-Bacterial Agents
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
beta-Lactamases
beta-Lactams
Biological and medical sciences
Colony Count, Microbial
Escherichia coli
Escherichia coli - drug effects
Escherichia coli Infections
Escherichia coli Infections - drug therapy
Escherichia coli Infections - microbiology
Experimental Therapeutics
Female
Humans
Klebsiella Infections
Klebsiella Infections - drug therapy
Klebsiella Infections - microbiology
Klebsiella pneumoniae
Klebsiella pneumoniae - drug effects
Lactams
Lactams - pharmacokinetics
Lactams - pharmacology
Lactams - therapeutic use
Medical sciences
Mice
Mice, Inbred ICR
Microbial Sensitivity Tests
Neutropenia
Pharmacology. Drug treatments
Thigh
Animal model
Carbapenem derivatives
Antibiotic
β-Lactams
Thigh
Escherichia coli
Bacteria
Antibacterial agent
Ertapenem
Biological activity
Klebsiella pneumoniae
Enterobacteriaceae
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Corresponding author. Mailing address: Center for Anti-Infective Research and Development, Hartford Hospital, 80 Seymour St., Hartford, CT 06102. Phone: (860) 545-3940. Fax: (860) 545-3992. E-mail: dnicola@harthosp.org.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.49.1.276-280.2005