The Role of Plant Innate Immunity in the Legume-Rhizobium Symbiosis

• Published in: Annual review of plant biology Vol. 68; no. 1; pp. 535 - 561
• Main Authors: Cao, Yangrong, Halane, Morgan K, Gassmann, Walter, Stacey, Gary
• Format: Journal Article
• Language: English
• Published: United States Annual Reviews 28.04.2017; Annual Reviews, Inc
• Subjects: Biological Evolution; Fabaceae - immunology; Fabaceae - microbiology; Immune response; Immune system; Immunity; Immunity, Innate; Immunology; Innate immunity; Legumes; Lipopolysaccharides - metabolism; Lipopolysaccharides - physiology; Mutualism; Nodules; Plant biology; Plant diseases; Plant immunity; plant innate immunity; Reactive Oxygen Species - metabolism; rhizobia; Rhizobium - physiology; Signal Transduction; Symbiosis; Symbiosis - immunology; Symbiosis - physiology; legumes; rhizobia; plant innate immunity; symbiosis
• ISSN: 1543-5008; 1545-2123
• DOI: 10.1146/annurev-arplant-042916-041030

A classic view of the evolution of mutualism is that it derives from a pathogenic relationship that attenuated over time to a situation in which both partners can benefit. If this is the case for rhizobia, then one might uncover features of the symbiosis that reflect this earlier pathogenic state. For example, as with plant pathogens, it is now generally assumed that rhizobia actively suppress the host immune response to allow infection and symbiosis establishment. Likewise, the host has retained mechanisms to control the nutrient supply to the symbionts and the number of nodules so that they do not become too burdensome. The open question is whether such events are strictly ancillary to the central symbiotic nodulation factor signaling pathway or are essential for rhizobial host infection. Subsequent to these early infection events, plant immune responses can also be induced inside nodules and likely play a role in, for example, nodule senescence. Thus, a balanced regulation of innate immunity is likely required throughout rhizobial infection, symbiotic establishment, and maintenance. In this review, we discuss the significance of plant immune responses in the regulation of symbiotic associations with rhizobia, as well as rhizobial evasion of the host immune system.