Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Telithromycin Transport

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Published inAntimicrobial Agents and Chemotherapy Vol. 50; no. 1; pp. 80 - 87
Main Authors YAMAGUCHI, Shoji, YING LAN ZHAO, NADAI, Masayuki, YOSHIZUMI, Hideo, XIAOBO CEN, TORITA, Shoko, TAKAGI, Kenji, TAKAGI, Kenzo, HASEGAWA, Takaaki
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.01.2006
Subjects
Animals
Anti-Bacterial Agents
Anti-Bacterial Agents - pharmacokinetics
Antibiotics, Antineoplastic - metabolism
Antibiotics. Antiinfectious agents. Antiparasitic agents
ATP Binding Cassette Transporter, Subfamily B, Member 1
ATP-Binding Cassette Transporters
ATP-Binding Cassette Transporters - metabolism
ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism
Biological and medical sciences
Biological Transport - physiology
Cell Line, Tumor
Doxorubicin - antagonists & inhibitors
Doxorubicin - pharmacokinetics
Drug Resistance, Multiple
Ketolides
Ketolides - pharmacokinetics
Liver
Liver - drug effects
Liver - metabolism
Liver - secretion
Mechanisms of Resistance
Medical sciences
Membrane Transport Proteins
Pharmacology. Drug treatments
Rats
Rats, Sprague-Dawley
Drug
Antibiotic
Multiple resistance
P Glycoprotein
Telithromycin
Antibacterial agent
Transport
Ketolide
Macrolide
ABC transporter
Multidrug resistance protein 2
Carrier protein
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Corresponding author. Mailing address: Department of Pharmacy and Pharmacokinetics, Aichi Medical University School of Medicine, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan. Phone: 81-561-63-1011. Fax: 81-561-63-1028. E-mail: takahase@aichi-med-u.ac.jp.
S.Y. and Y.L.Z. contributed equally to this work.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.50.1.80-87.2006