Label-free, non-contact, in-vivo ophthalmic imaging using photoacoustic remote sensing microscopy

We present the first label-free, non-contact, in-vivo imaging of the ocular vasculature using photoacoustic remote sensing (PARS) microscopy. Both anterior and posterior segments mouse eye were imaged. Vasculature of iris, sclera and retina tissues were clearly resolved. To best of our knowledge thi...

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Bibliographic Details
Published inarXiv.org
Main Authors Hosseinaee, Zohreh, Khalili, Layla, Tummon Simmons, James Alex, Bell, Kevan, Parsin Haji Reza
Format Paper Journal Article
LanguageEnglish
Published Ithaca Cornell University Library, arXiv.org 13.09.2020
Subjects
Eye diseases
Medical imaging
Microscopy
Physics - Medical Physics
Remote sensing
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Summary:We present the first label-free, non-contact, in-vivo imaging of the ocular vasculature using photoacoustic remote sensing (PARS) microscopy. Both anterior and posterior segments mouse eye were imaged. Vasculature of iris, sclera and retina tissues were clearly resolved. To best of our knowledge this the first study showing non-contact photoacoustic imaging conducted on in-vivo ocular tissue. We believe that PARS microscopy has the potential to advance the diagnosis and treatment of ocular diseases.
ISSN:2331-8422
DOI:10.48550/arxiv.2009.06088