Shear-driven instabilities of membrane tubes and dynamin-induced scission

Motivated by the mechanics of dynamin-mediated membrane tube fission we analyse the stability of fluid membrane tubes subjected to shear flow in azimuthal direction. We find a novel helical instability driven by the membrane shear flow which results in a non-equilibrium steady state for the tube flu...

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Bibliographic Details
Published inarXiv.org
Main Authors Al-Izzi, Sami C, Sens, Pierre, Turner, Matthew S
Format Paper Journal Article
LanguageEnglish
Published Ithaca Cornell University Library, arXiv.org 15.06.2020
Subjects
Cleavage
Fission
Flow stability
Membranes
Physics - Biological Physics
Physics - Soft Condensed Matter
Shear flow
Stability analysis
Tubes
Variation
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Summary:Motivated by the mechanics of dynamin-mediated membrane tube fission we analyse the stability of fluid membrane tubes subjected to shear flow in azimuthal direction. We find a novel helical instability driven by the membrane shear flow which results in a non-equilibrium steady state for the tube fluctuations. This instability has its onset at shear rates that may be physiologically accessible under the action of dynamin and could also be probed using in-vitro experiments on membrane nanotubes, e.g. using magnetic tweezers. We discuss how such an instability may play a role in the mechanism for dynamin-mediated membrane tube fission.
ISSN:2331-8422
DOI:10.48550/arxiv.1810.05862