Pharmacology and Pharmacokinetics of the Antiviral Agent β-d-2′,3′-Dideoxy-3′-Oxa-5-Fluorocytidine in Cells and Rhesus Monkeys

• Published in: Antimicrobial Agents and Chemotherapy Vol. 49; no. 7; pp. 2589 - 2597
• Main Authors: Hernandez-Santiago, Brenda I, Chen, Huachun, Asif, Ghazia, Beltran, Thierry, Mao, Shuli, Hurwitz, Selwyn J, Grier, Jason, McClure, Harold M, Chu, Chung K, Liotta, Dennis C, Schinazi, Raymond F
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.07.2005
• Subjects: Animals; Antiviral Agents; Antiviral Agents - administration & dosage; Antiviral Agents - metabolism; Antiviral Agents - pharmacokinetics; Antiviral Agents - toxicity; Cell Line, Tumor; Cytidine; Cytidine - administration & dosage; Cytidine - analogs & derivatives; Cytidine - metabolism; Cytidine - pharmacokinetics; Cytidine - toxicity; Escherichia coli; Escherichia coli - enzymology; Female; Hepatitis B virus; Human immunodeficiency virus 1; Human immunodeficiency virus 2; Humans; Leukocytes, Mononuclear - metabolism; Macaca mulatta; Male; Mice; Simian immunodeficiency virus; Thymidine Phosphorylase - metabolism
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.49.7.2589-2597.2005

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