Aggregation of Therapeutic Proteins

This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its c...

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Bibliographic Details
Main Authors Wang, Wei, Roberts, Christopher J
Format eBook Book
LanguageEnglish
Published Hoboken, N.J Wiley 2010
John Wiley & Sons, Incorporated
Wiley-Blackwell
Edition1. Aufl.
Subjects
Aggregation (Chemistry)
Cell Aggregation
Development
Drug Discovery
MEDICAL
Pharmacology
Protein Conformation
Protein drugs
Protein Folding
Recombinant Proteins > metabolism
Recombinant Proteins > therapeutic use
Gesundheit Sonstiges
Medizin
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Summary:This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.
Bibliography:Includes bibliographical references and index
ISBN:0470411961
9780470411964
0470769815
9780470769812
0470769823
9780470769829
DOI:10.1002/9780470769829