High-Level Resistance to Trimethoprim in Clinical Isolates of Campylobacter jejuni by Acquisition of Foreign Genes (dfr1 and dfr9) Expressing Drug-Insensitive Dihydrofolate Reductases

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Published inAntimicrobial Agents and Chemotherapy Vol. 42; no. 12; pp. 3059 - 3064
Main Authors Gibreel, Amera, Sköld, Ola
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.12.1998
Subjects
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Campylobacter jejuni
Campylobacter jejuni - drug effects
Campylobacter jejuni - enzymology
Campylobacter jejuni - genetics
Campylobacter jejuni - isolation & purification
Chromosome Mapping
Chromosomes, Bacterial - genetics
DNA, Bacterial - genetics
DNA, Bacterial - isolation & purification
Genes, Bacterial
Genes, Bacterial - genetics
Humans
Mechanisms of Resistance
Medical sciences
Microbial Sensitivity Tests
Pharmacology. Drug treatments
Polymerase Chain Reaction
Tetrahydrofolate Dehydrogenase
Tetrahydrofolate Dehydrogenase - genetics
Tetrahydrofolate Dehydrogenase - metabolism
Trimethoprim Resistance
Trimethoprim Resistance - genetics
Enzyme
Campylobacteraceae
Transposon
Trimethoprim
Gene expression
Campylobacter jejuni
Polymerase chain reaction
Microorganism resistance
Minimum inhibitory concentration
Bacteria
Antiinfectious
Oxidoreductases
Dihydrofolate reductase
Mutation
Molecular cloning
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Corresponding author. Mailing address: Division of Microbiology, Department of Pharmaceutical Biosciences, P.O. Box 581, Biomedical Center, Uppsala University, S-751 23 Uppsala, Sweden. Phone: 46-18-4714500. Fax: 46-18-502790. E-mail: ola.skold@farmbio.uu.se.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.42.12.3059