Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

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Bibliographic Details
Published inAntimicrobial Agents and Chemotherapy Vol. 41; no. 11; pp. 2333 - 2338
Main Authors ABRUZZO, G. K, FLATTERY, A. M, KROPP, H, BARTIZAL, K, GILL, C. J, KONG, L, SMITH, J. G, PIKOUNIS, V. B, BALKOVEC, J. M, BOUFFARD, A. F, DROPINSKI, J. F, ROSEN, H
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.11.1997
Subjects
Administration, Oral
Animals
Anti-Bacterial Agents
Anti-Bacterial Agents - therapeutic use
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal Agents
Antifungal Agents - therapeutic use
Aspergillosis
Aspergillosis - drug therapy
Biological and medical sciences
Candidiasis
Candidiasis - drug therapy
Cryptococcosis
Cryptococcosis - drug therapy
Disease Models, Animal
Drug Evaluation, Preclinical
Echinocandins
Female
Injections, Intraperitoneal
Kidney Diseases - drug therapy
Lipopeptides
Medical sciences
Mice
Mice, Inbred DBA
Peptides
Peptides, Cyclic
Pharmacology. Drug treatments
Candida albicans
Yeast
Cryptococcus neoformans
Glycosyltransferases
Fungi
Antifungal agent
Fungi Imperfecti
Thallophyta
Enzyme
Transferases
Rodentia
Single dose
Enzyme inhibitor
1,3-β-Glucan synthase
Biological activity
Parenteral administration
Infection
In vivo
Vertebrata
Mammalia
Mouse
Animal
Hexosyltransferases
Aspergillus fumigatus
Pharmacokinetics
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Summary:Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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ISSN:0066-4804
1098-6596
DOI:10.1128/aac.41.11.2333