HIV-1 Protease Codon 36 Polymorphisms and Differential Development of Resistance to Nelfinavir, Lopinavir, and Atazanavir in Different HIV-1 Subtypes

• Published in: Antimicrobial Agents and Chemotherapy Vol. 54; no. 7; pp. 2878 - 2885
• Main Authors: Lisovsky, Irene, Schader, Susan M., Martinez-Cajas, Jorge-Luis, Oliveira, Maureen, Moisi, Daniela, Wainberg, Mark A.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.07.2010; American Society for Microbiology (ASM)
• Subjects: Anti-HIV Agents; Anti-HIV Agents - pharmacology; Anti-HIV Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Atazanavir Sulfate; Biological and medical sciences; Cell Line; Cells, Cultured; Codon; Codon - genetics; Genotype; HIV Infections - drug therapy; HIV Infections - genetics; HIV Infections - virology; HIV Protease; HIV Protease - genetics; HIV-1; HIV-1 - drug effects; HIV-1 - enzymology; HIV-1 - physiology; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Lopinavir; Medical sciences; Nelfinavir - therapeutic use; Oligopeptides - therapeutic use; Pharmacology. Drug treatments; Polymorphism, Genetic; Polymorphism, Genetic - genetics; Pyridines - therapeutic use; Pyrimidinones - therapeutic use; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Antiretroviral agent; Genetic variability; HIV-1 virus; Codon; Nelfinavir; Development; Antiviral; Immunopathology; Atazanavir; Typing; Enzyme; Lopinavir; Enzyme inhibitor; Retroviridae; Genotype; AIDS; Immune deficiency; Lentivirus; Infection; Virus; Resistance; Peptidases; Viral disease; Hydrolases; Human immunodeficiency virus; Subtype; Protease inhibitor; Polymorphism
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.01828-09

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