Proteomic Signature of Fatty Acid Biosynthesis Inhibition Available for In Vivo Mechanism-of-Action Studies

• Published in: Antimicrobial Agents and Chemotherapy Vol. 55; no. 6; pp. 2590 - 2596
• Main Authors: WENZEL, Michaela, PATRA, Malay, ALBRECHT, Dirk, CHEN, David Y.-K, NICOLAOU, K. C, METZLER-NOLTE, Nils, BANDOW, Julia E
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.06.2011
• Subjects: Adamantane; Adamantane - pharmacology; Aminobenzoates; Aminobenzoates - pharmacology; Aminophenols; Aminophenols - pharmacology; Anilides; Anilides - pharmacology; Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacology; Antibiotics; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobial agents; Bacillus subtilis; Bacillus subtilis - drug effects; Bacillus subtilis - metabolism; Bacterial Proteins; Bacterial Proteins - biosynthesis; Biological and medical sciences; cerulenin; Chromium; Drug Discovery; Enzymes; Fatty Acids; Fatty Acids - biosynthesis; Mechanisms of Action: Physiological Effects; Medical sciences; Pharmacology. Drug treatments; Polycyclic Compounds; Polycyclic Compounds - pharmacology; Proteomics; Structure-activity relationships; Triclosan; In vivo; Proteomics; Lipids; Biosynthesis; Inhibitor; Inhibition; Mechanism of action; Fatty acids
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00078-11

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