Is the Recommended Dose of Efavirenz Optimal in Young West African Human Immunodeficiency Virus-Infected Children?

• Published in: Antimicrobial Agents and Chemotherapy Vol. 53; no. 10; pp. 4407 - 4413
• Main Authors: HIRT, Déborah, URIEN, Saik, VAN DE PERRE, Philippe, TRELUYER, Jean-Marc, OLIVIER, Mathieu, PEYRIERE, Hélène, NACRO, Boubacar, DIAGBOUGA, Serge, ZOURE, Emmanuelle, ROUET, François, HIEN, Hervé, MSELLATI, Philippe
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.10.2009; American Society for Microbiology (ASM)
• Subjects: Adolescent; Age; Anti-HIV Agents; Anti-HIV Agents - administration & dosage; Anti-HIV Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Benzoxazines; Benzoxazines - administration & dosage; Benzoxazines - therapeutic use; Biological and medical sciences; Body weight; Child; Child, Preschool; Children; Chromatography, High Pressure Liquid; Drug Administration Schedule; Efavirenz; Female; High-performance liquid chromatography; HIV Infections; HIV Infections - drug therapy; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunodeficiency; Immunopathology; Infectious diseases; Male; Medical sciences; Pharmacokinetics; Pharmacology; Pharmacology. Drug treatments; RNA; RNA viruses; Toxicity; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Human; Immunopathology; Antiretroviral agent; Benzoxazine derivatives; RNA-directed DNA polymerase; Acetylenic compound; Enzyme; Non nucleoside compound; Transferases; Enzyme inhibitor; AIDS; Immune deficiency; Efavirenz; African; Infection; Allosteric inhibitor; Nucleotidyltransferases; Reverse transcriptase inhibitor; Viral disease; Antiviral; Dose; Child
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01594-08

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