Subclinical hypothyroidism: a modifiable risk factor for depression?

The authors assessed the lifetime history of major depression in 16 subjects with subclinical hypothyroidism and 15 subjects whose thyroid function was completely normal. The lifetime frequency of depression was significantly higher in the subjects who met the criteria for subclinical hypothyroidism...

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Bibliographic Details
Published inThe American journal of psychiatry Vol. 150; no. 3; p. 508
Main Authors Haggerty, Jr, J J, Stern, R A, Mason, G A, Beckwith, J, Morey, C E, Prange, Jr, A J
Format Journal Article
LanguageEnglish
Published United States 01.03.1993
Subjects
Adult
Comorbidity
Depressive Disorder - complications
Depressive Disorder - epidemiology
Female
Humans
Hypothyroidism - complications
Hypothyroidism - epidemiology
Prevalence
Risk Factors
Thyroid Function Tests
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Summary:The authors assessed the lifetime history of major depression in 16 subjects with subclinical hypothyroidism and 15 subjects whose thyroid function was completely normal. The lifetime frequency of depression was significantly higher in the subjects who met the criteria for subclinical hypothyroidism (56%) than in those who did not (20%), suggesting that subclinical hypothyroidism may lower the threshold for the occurrence of depression.
ISSN:0002-953X
DOI:10.1176/ajp.150.3.508