Trioxaquines and Heme-Artemisinin Adducts Inhibit the In Vitro Formation of Hemozoin Better than Chloroquine

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Published inAntimicrobial Agents and Chemotherapy Vol. 51; no. 10; pp. 3768 - 3770
Main Authors Loup, Christophe, Lelièvre, Joël, Benoit-Vical, Françoise, Meunier, Bernard
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.10.2007
Subjects
Alkylation
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antimalarials
Antimalarials - pharmacology
Artemisinins
Artemisinins - chemistry
Artemisinins - pharmacology
Biological and medical sciences
Chloroquine
Chloroquine - pharmacology
Dioxanes
Dioxanes - chemistry
Dioxanes - pharmacology
Heme
Heme - chemistry
Hemeproteins
Hemeproteins - antagonists & inhibitors
Hemeproteins - biosynthesis
Mechanisms of Action: Physiological Effects
Medical sciences
Pharmacology. Drug treatments
Plasmodium - drug effects
Plasmodium - enzymology
Sesquiterpenes - pharmacology
Spectrophotometry, Infrared
Antimalarial
Chloroquine
Hemozoin
Artemisinin
Heme
Parasiticide
Inhibitor
Antirheumatic agent
In vitro
Molecular adduct
Adduct
Trioxaquine derivatives
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Corresponding author. Mailing address for Christophe Loup: Laboratoire de Chimie de Coordination, CNRS, 205 Route de Narbonne, 31000 Toulouse cedex 4, France. Phone: 33 5 61 33 31 48. Fax: 33 5 61 32 20 96. E-mail: christophe.loup@lcc-toulouse.fr. Mailing address for Françoise Benoit-Vical: CHU Rangueil, Service de Parasitologie et Mycologie, 1 Av. Jean Poulhès, TSA 50032, 31059 Toulouse cedex 9, France. Phone: 33 5 61 32 34 46. Fax: 33 5 61 32 20 96. E-mail: francoise.vical@toulouse.inserm.fr
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00239-07