Thymidine Kinase Mutations Conferring Acyclovir Resistance in Herpes Simplex Type 1 Recombinant Viruses

• Published in: Antimicrobial Agents and Chemotherapy Vol. 50; no. 11; pp. 3889 - 3892
• Main Authors: SERGERIE, Yan, BOIVIN, Guy
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.11.2006
• Subjects: Acyclovir; Acyclovir - pharmacology; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - pharmacology; Biological and medical sciences; Cercopithecus aethiops; Cosmids - genetics; DNA, Viral - genetics; DNA-Directed DNA Polymerase - genetics; Genotype; Herpes simplex virus 1; Herpesvirus 1, Human; Herpesvirus 1, Human - drug effects; Kinetics; Medical sciences; Mutation - genetics; Pharmacology. Drug treatments; Phenotype; Plasmids - genetics; Thymidine Kinase; Thymidine Kinase - genetics; Vero Cells; Virus Replication - drug effects; Thymidine kinase; Acyclic nucleoside; Purine nucleoside; Enzyme; Herpesviridae; Transferases; Alphaherpesvirinae; Virus; Resistance; Aciclovir; Nucleoside analog; Antiviral; Genetics; Human herpesvirus 1; Mutation; Recombinant protein
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00889-06

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