Pharmacokinetics and Distribution over the Blood-Brain Barrier of Zalcitabine (2′,3′-Dideoxycytidine) and BEA005 (2′,3′-Dideoxy-3′-Hydroxymethylcytidine) in Rats, Studied by Microdialysis

• Published in: Antimicrobial Agents and Chemotherapy Vol. 42; no. 9; pp. 2174 - 2177
• Main Authors: BORG, N, STAHLE, L
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.09.1998
• Subjects: AIDS/HIV; Animals; Anti-HIV Agents; Anti-HIV Agents - pharmacokinetics; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Biological and medical sciences; Blood-Brain Barrier; Brain; Brain - metabolism; Cytidine; Cytidine - analogs & derivatives; Cytidine - pharmacokinetics; Male; Medical sciences; Microdialysis; Pharmacology. Drug treatments; Rats; Rats, Sprague-Dawley; Zalcitabine; Zalcitabine - pharmacokinetics; Rat; Zalcitabine; Central nervous system; Blood brain barrier; Blood plasma; Antiviral; Subcutaneous administration; Muscle; Pyrimidine nucleoside; Rodentia; Elimination; Retroviridae; Bioavailability; Lentivirus; Virus; Vertebrata; Biological fixation; Mammalia; Microdialysis; Animal; Dideoxynucleoside; Distribution; Human immunodeficiency virus; Pharmacokinetics; Brain (vertebrata)
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.42.9.2174

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC