Effects of Agave Fructans, Inulin, and Starch on Metabolic Syndrome Aspects in Healthy Wistar Rats

• Published in: ACS omega Vol. 5; no. 19; pp. 10740 - 10749
• Main Authors: Regalado-Rentería, Evelyn, Aguirre-Rivera, Juan Rogelio, Godínez-Hernández, César Iván, García-López, Juan Carlos, Oros-Ovalle, A. Cuauhtémoc, Martínez-Gutiérrez, Fidel, Martinez-Martinez, Marco, Ratering, Stefan, Schnell, Sylvia, Ruíz-Cabrera, Miguel Ángel, Juárez-Flores, Bertha Irene
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 19.05.2020
• ISSN: 2470-1343; 2470-1343
• DOI: 10.1021/acsomega.0c00272

Healthy Wistar rats were supplemented during 20 weeks with commercial inulin (I) and Agave tequilana fructans (CAT), experimental fructans from A. tequilana (EAT) and A. salmiana (AS) mature stems, rice starch 10% (RS), and standard feed for rodents (C). Feed intake was kept steady, but with I, body weight and abdominal adipose tissue (6.01 g) decreased at the end. Glucose (mg/dL) (C, 120.52; I, 110.69; CAT, 105.75; EAT, 115.48; AS, 101.63; and RS, 121.82), total cholesterol (C, 89.89; I, 64.48; CAT, 68.04; EAT, 68.74; AS, 68.04; and RS, 82), and triglycerides (C, 84.03; I, 59.52; CAT, 68.56; EAT, 59.08; AS, 75.27; and RS, 81.8) kept being normal and without differences between fructans. At the end, there was a significant increase in lactic acid bacteria when the I and AS groups were compared to the C group (C, 9.18; I, 10.64; CAT, 10.34; EAT, 10.36; AS, 10.49; and RS, 9.62 log 10 CFU/g of feces). In addition, with fructans, there was an accelerated process in feces emptiness, Lieberkühn crypts kept their morphology, and there was an increment of goblet cells.