Efficacy of Cefepime and Imipenem in Experimental Murine Pneumonia Caused by Porin-Deficient Klebsiella pneumoniae Producing CMY-2 β-Lactamase

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Published inAntimicrobial Agents and Chemotherapy Vol. 49; no. 8; pp. 3311 - 3316
Main Authors Pichardo, Cristina, Rodríguez-Martínez, José Manuel, Pachón-Ibañez, María E, Conejo, Carmen, Ibáñez-Martínez, José, Martínez-Martínez, Luis, Pachón, Jerónimo, Pascual, Álvaro
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.08.2005
Subjects
Animals
Anti-Bacterial Agents
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
beta-Lactamases
beta-Lactamases - biosynthesis
Cephalosporins
Cephalosporins - pharmacokinetics
Cephalosporins - pharmacology
Cephalosporins - therapeutic use
Disease Models, Animal
Experimental Therapeutics
Female
Humans
Imipenem
Imipenem - pharmacokinetics
Imipenem - pharmacology
Imipenem - therapeutic use
Klebsiella Infections - drug therapy
Klebsiella Infections - microbiology
Klebsiella pneumoniae
Klebsiella pneumoniae - drug effects
Klebsiella pneumoniae - enzymology
Klebsiella pneumoniae - genetics
Mice
Mice, Inbred C57BL
Microbial Sensitivity Tests
Pneumonia, Bacterial
Pneumonia, Bacterial - drug therapy
Pneumonia, Bacterial - microbiology
Porins - deficiency
Porins - genetics
Treatment Outcome
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
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Present address: Service of Microbiology, University Hospital Marqués de Valdecilla, Santander, Spain.
Corresponding author. Mailing address: Department of Microbiology, School of Medicine, University of Seville, Apdo. 914, 41080 Seville, Spain. Phone: 34-95-455-2863. Fax: 34-95-437-7413. E-mail: apascual@us.es.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.49.8.3311-3316.2005