Characteristics and immune functions of the endogenous CRISPR-Cas systems in myxobacteria

• Published in: mSystems Vol. 9; no. 6; p. e0121023
• Main Authors: Hu, Wei-feng, Yang, Jiang-yu, Wang, Jing-jing, Yuan, Shu-fei, Yue, Xin-jing, Zhang, Zheng, Zhang, Ya-qi, Meng, Jun-yan, Li, Yue-zhong
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 18.06.2024
• Subjects: Bacteriology; Clustered Regularly Interspaced Short Palindromic Repeats - genetics; CRISPR; CRISPR-Cas; CRISPR-Cas Systems - genetics; Datasets; DNA repair; Genes; Genetic engineering; Genome, Bacterial - genetics; Genomes; Gram-negative bacteria; Homology; Immune system; immunity; myxobacteria; Myxococcales - genetics; Myxococcus xanthus; Phages; Phylogeny; Plasmids; Prokaryotes; Proteins; Research Article; Social behavior; Social organization; target tracing; CRISPR-Cas; immunity; Myxococcus xanthus; target tracing; myxobacteria

Serving as an adaptive immune system, clustered regularly interspaced short palindromic repeats and their associated proteins (CRISPR-Cas) empower prokaryotes to fend off the intrusion of external genetic materials. Myxobacteria are a collective of swarming Gram-stain-negative predatory bacteria dis...