Composition and Antimicrobial Activity of the Essential Oils of Micromeria cristata subsp. phrygia and the Enantiomeric Distribution of Borneol

• Published in: Journal of agricultural and food chemistry Vol. 49; no. 9; pp. 4300 - 4303
• Main Authors: Tabanca, Nurhayat, Kırımer, Neşe, Demirci, Betül, Demirci, Fatih, Başer, K. Hüsnü Can
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01.09.2001
• Subjects: Agronomy. Soil science and plant productions; Biological and medical sciences; Bornanes; Colony Count, Microbial; Fundamental and applied biological sciences. Psychology; Gas Chromatography-Mass Spectrometry; General agronomy. Plant production; General pharmacology; Generalities. Agricultural and farming systems. Agricultural development; Generalities. Production, biomass, yield. Quality; Gram-Negative Bacteria - drug effects; Gram-Positive Bacteria - drug effects; Lamiaceae - chemistry; Medical sciences; Microbial Sensitivity Tests; Oils, Volatile - analysis; Oils, Volatile - pharmacology; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Endemic species; Labiatae; Essential oil plant; Dicotyledones; Enantiomer; Angiospermae; Spermatophyta; Chemical composition; Essential oil; Biological activity; Antimicrobial agent; Medicinal plant
• ISSN: 0021-8561; 1520-5118
• DOI: 10.1021/jf0105034

Water-distilled essential oils from herbal parts of Micromeria cristata (Hampe) Griseb. subsp. phrygia P. H. Davis (Endemic) (Lamiaceae) collected from three different localities were analyzed by GC-MS. The major component characterized in the three oils was borneol (27−39%). Other main components were determined as camphor (9−15%), caryophyllene oxide (4−6%), and trans-verbenol (4−6%) in the oils. Enantiomeric distributions of borneol and camphor in the oils were determined on a fused silica Lipodex-E capillary column using a multidimensional GC-MS system. The three essential oils and both enantiomers of borneol have been evaluated for their antimicrobial activity. They showed inhibitory effects on Gr (−) and Gr (+) pathogenic microorganisms. Keywords: Micromeria cristata subsp. phrygia; essential oils; enantiomeric distribution; borneol; GC-MS; MD-GC-MS; antimicrobial activity