Synthesis of Glycopeptides Containing Carbohydrate and Peptide Recognition Motifs

The synthesis of glycopeptides is demanding because of the polyfunctionality of the target molecules. A simple calculation reveals up to 10 different functionalities that can be encountered during the synthesis of a glcopeptide.

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Bibliographic Details
Published inChemical reviews Vol. 100; no. 12; pp. 4495 - 4538
Main Authors Herzner, Holger, Reipen, Tanja, Schultz, Michael, Kunz, Horst
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 01.12.2000
Subjects
Amino acids
Antigens
Biochemistry
Biosynthesis
Carbohydrates
Catalysis
Chemical bonds
Collagen
Gallium compounds
Molecules
Peptides
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Summary:The synthesis of glycopeptides is demanding because of the polyfunctionality of the target molecules. A simple calculation reveals up to 10 different functionalities that can be encountered during the synthesis of a glcopeptide.
Bibliography:ark:/67375/TPS-WC3LKL8Z-B
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ISSN:0009-2665
1520-6890
DOI:10.1021/cr990308c