Polyelectrolyte-Coated Gold Magnetic Nanoparticles for Immunoassay Development: Toward Point of Care Diagnostics for Syphilis Screening

• Published in: Analytical chemistry (Washington) Vol. 85; no. 14; pp. 6688 - 6695
• Main Authors: Yang, Dong, Ma, Jianzhong, Zhang, Qinlu, Li, Ningning, Yang, Jiangcun, Raju, Paul Ananda, Peng, Mingli, Luo, Yanling, Hui, Wenli, Chen, Chao, Cui, Yali
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 16.07.2013
• Subjects: Antibodies; Antigens; Diagnostic software; Disease control; Gold; Immunoassay; Immunoassay - methods; Infectious diseases; Mass Screening - methods; Metal Nanoparticles; Nanoparticles; Particulate composites; Point-of-Care Systems; Polymers; Syphilis; Syphilis - blood; Syphilis - diagnosis; Thermogravimetric analysis; Treponema pallidum; Ultraviolet radiation

Immediate response for disease control relies on simple, inexpensive, and sensitive diagnostic tests, highly sought after for timely and accurate test of various diseases, including infectious diseases. Composite Fe3O4/Au nanoparticles have attracted considerable interest in diagnostic applications...