Dioxins and Nonortho PCBs in Breast Milk of Vietnamese Mothers Living in the Largest Hot Spot of Dioxin Contamination

• Published in: Environmental science & technology Vol. 49; no. 9; pp. 5732 - 5742
• Main Authors: Nghi, Tran Ngoc, Nishijo, Muneko, Manh, Ho Dung, Tai, Pham The, Van Luong, Hoang, Anh, Tran Hai, Thao, Pham Ngoc, Trung, Nguyen Viet, Waseda, Tomoo, Nakagawa, Hideaki, Kido, Teruhiko, Nishijo, Hisao
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 05.05.2015
• Subjects: Adult; breast milk; Breastfeeding & lactation; Chemical compounds; Contamination; Dioxins; Dioxins - analysis; Eating; Environmental Pollutants - analysis; exposure assessment; Female; food intake; Geography; hospitals; Humans; Infant, Newborn; Lipids; Male; Milk, Human - chemistry; Mothers; neonates; Parity; PCB; Polychlorinated biphenyls; Polychlorinated Biphenyls - analysis; Polychlorinated Dibenzodioxins - analysis; Pregnancy; Regression Analysis; Residence Characteristics; risk factors; tetrachlorodibenzo-p-dioxin; Vietnam; Vietnam; ISEW, Vietnam
• ISSN: 0013-936X; 1520-5851; 1520-5851
• DOI: 10.1021/es506211p

Bien Hoa Air Base is the largest dioxin contamination hot spot in Vietnam. In 2012, we recruited 216 mothers who were living in 10 communities around Bien Hoa Air Base and had delivered newborns at a prefecture hospital, and we investigated recent exposure levels of dioxins and nonortho PCBs in their breast milk. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-tetraCDD) was present at 2.6 pg/g lipid in primiparae and 2.2 pg/g lipid in multiparae. Among multiparae and total subjects, significant high prevalence of 2,3,7,8-tetraCDD ≥ 5 pg/g lipid and 2,3,7,8-tetraCDD contribution ≥ 40% were observed in mothers living in the five communities closest to Bien Hoa Air Base. The TEQ for nonortho PCBs was 1.6 pg-TEQ/g lipid for primiparae, and this was even lower than that in the unsprayed area. The length of residency was a strong factor to increase dioxins, including 2,3,7,8-tetraCDD. Residency in the five communities with the highest exposure was a specific risk factor for increased 2,3,7,8-tetraCDD in breast milk. Food intake might contribute partly to the increased levels of dioxin congeners other than 2,3,7,8-tetraCDD in breast milk. These results suggest that Bien Hoa Air Base has led to elevated 2,3,7,8-tetraCDD levels in breast milk of mothers in nearby areas even in the recent years.