Urinary Concentrations and Antibacterial Activities of Nitroxoline at 250 Milligrams versus Trimethoprim at 200 Milligrams against Uropathogens in Healthy Volunteers

• Published in: Antimicrobial Agents and Chemotherapy Vol. 58; no. 2; pp. 713 - 721
• Main Authors: WAGENLEHNER, Florian M. E, MÜNCH, Fabian, NABER, Kurt G, PILATZ, Adrian, BÄRMANN, Birte, WEIDNER, Wolfgang, WAGENLEHNER, Christine M, STRAUBINGER, Marion, BLENK, Holger, PFISTER, Wolfgang, KRESKEN, Michael
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.02.2014
• Subjects: Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - urine; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial Infections; Biological and medical sciences; Cross-Over Studies; Drug Administration Schedule; Escherichia coli; Escherichia coli - drug effects; Escherichia coli - growth & development; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Klebsiella pneumoniae; Klebsiella pneumoniae - drug effects; Klebsiella pneumoniae - growth & development; Medical sciences; Microbial Sensitivity Tests; Nitroquinolines; Nitroquinolines - pharmacokinetics; Nitroquinolines - urine; Pharmacology; Pharmacology. Drug treatments; Proteus mirabilis; Proteus mirabilis - drug effects; Proteus mirabilis - growth & development; Staphylococcus saprophyticus; Staphylococcus saprophyticus - drug effects; Staphylococcus saprophyticus - growth & development; Trimethoprim; Trimethoprim - pharmacokinetics; Trimethoprim - urine; Urinary Tract Infections; Antifolate; Human; Healthy subject; Antiseptic; Quinoline derivatives; Trimethoprim; Pyrimidine derivatives; Antiinfectious; Concentration; Antibacterial agent; Comparative study; Nitroxoline
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.02147-13

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