SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide

• Published in: Antimicrobial Agents and Chemotherapy Vol. 53; no. 3; pp. 1013 - 1018
• Main Authors: NAITO, Takeshi, IZUMI, Kazuki, MATSUOKA, Masao, KODAMA, Eiichi, SAKAGAMI, Yasuko, KAJIWARA, Keiko, NISHIKAWA, Hiroki, WATANABE, Kentaro, SARAFIANOS, Stefan G, OISHI, Shinya, FUJII, Nobutaka
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.03.2009; American Society for Microbiology (ASM)
• Subjects: Amino Acid Sequence; Amino Acid Substitution - drug effects; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Biological and medical sciences; Circular Dichroism; Drug Resistance, Viral; Drug Resistance, Viral - drug effects; Drug Resistance, Viral - genetics; HeLa Cells; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Fusion Inhibitors - chemistry; HIV Fusion Inhibitors - pharmacology; HIV-1; HIV-1 - drug effects; HIV-1 - genetics; HIV-1 - physiology; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Medical sciences; Molecular Sequence Data; Peptide Fragments; Peptides; Peptides - chemistry; Peptides - pharmacology; Pharmacology. Drug treatments; Protein Structure, Secondary - genetics; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virus Replication; Virus Replication - drug effects; Immunopathology; Antiretroviral agent; Peptides; HIV-1 virus; Retroviridae; AIDS; Immune deficiency; Lentivirus; Fusion inhibitor; Infection; Virus; Resistance; Enfuvirtide; Viral disease; Antiviral; Replication; Human immunodeficiency virus; Mutation
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01211-08

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