Ampicillin-Resistant Non-β-Lactamase-Producing Haemophilus influenzae in Spain: Recent Emergence of Clonal Isolates with Increased Resistance to Cefotaxime and Cefixime

• Published in: Antimicrobial Agents and Chemotherapy Vol. 51; no. 7; pp. 2564 - 2573
• Main Authors: GARCIA-COBOS, Silvia, CAMPOS, José, LAZARO, Edurne, ROMAN, Federico, CERCENADO, Emilia, GARCIA-REY, César, PEREZ-VAZQUEZ, Maria, OTEO, Jesus, DE ABAJO, Francisco
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.07.2007; American Society for Microbiology (ASM)
• Subjects: Amino Acid Substitution; Ampicillin Resistance; Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; beta-Lactamases; beta-Lactamases - metabolism; Biological and medical sciences; Cefixime; Cefixime - pharmacology; Cefotaxime; Cefotaxime - pharmacology; Cephalosporin Resistance; DNA, Bacterial - analysis; DNA, Bacterial - genetics; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Haemophilus influenzae; Haemophilus influenzae - drug effects; Haemophilus influenzae - enzymology; Haemophilus influenzae - genetics; Haemophilus influenzae - isolation & purification; Haemophilus influenzae - metabolism; Histidine - metabolism; Humans; Lysine - metabolism; Mechanisms of Resistance; Medical sciences; Microbial Sensitivity Tests; Molecular Epidemiology - methods; Pharmacology. Drug treatments; Polymerase Chain Reaction; Sequence Analysis, DNA; Spain - epidemiology; Europe; Spain; Cefotaxime; Enzyme; β-Lactams; β-Lactamase; Epidemiology; Haemophilus influenzae; Pasteurellaceae; Resistance; Cephalosporin derivatives; Antibiotic; Bacteria; Hydrolases; Isolate; Antibacterial agent; Cefixime
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00354-07

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