Characterization of human tibrovirus envelope glycoproteins

• Published in: Journal of Virology Vol. 98; no. 7; p. e0049924
• Main Authors: Munyeku-Bazitama, Yannick, Saito, Takeshi, Hattori, Takanari, Miyamoto, Hiroko, Lombe, Boniface Pongombo, Mori-Kajihara, Akina, Kajihara, Masahiro, Muyembe-Tamfum, Jean-Jacques, Igarashi, Manabu, Park, Eun-sil, Morikawa, Shigeru, Makiala-Mandanda, Sheila, Takada, Ayato
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 23.07.2024
• Subjects: Amino Acid Sequence; Animals; Antibodies, Viral - immunology; Cell Line; Glycosylation; HEK293 Cells; Humans; Mice; Mucin-1 - metabolism; Viral Envelope Proteins - genetics; Viral Envelope Proteins - metabolism; Viral Tropism; Virology; Virus Internalization; Virus-Cell Interactions; Ekpoma virus 2; Ekpoma virus 1; glycoprotein; Mundri virus; Bas-Congo virus; Tibrogargan virus; tibrovirus

Human tibroviruses are poorly characterized emerging rhabdoviruses associated with either asymptomatic infection or severe disease with a case fatality rate as high as 60% in humans. However, the extent and burden of human infection as well as factors behind differences in infection outcomes are lar...