Increased Feline Cerebral Blood Flow Induced by Dehydroevodiamine Hydrochloride from Evodia rutaecarpa
Dehydroevodiamine hydrochloride (0.1-0.3 mg/kg iv), which was isolated from the leaves of Evodia rutaecarpa, increased the cerebral blood flow recorded from the surface of the supra-sylvian gyrus in anesthetized cats. This action reached a maximum 1-4 min after injection and continued for 10 min. Ho...
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| Published in | Journal of natural products (Washington, D.C.) Vol. 57; no. 3; pp. 387 - 389 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Washington, DC
American Chemical Society
01.03.1994
Glendale, AZ American Society of Pharmacognosy |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Dehydroevodiamine hydrochloride (0.1-0.3 mg/kg iv), which was isolated from the leaves of Evodia rutaecarpa, increased the cerebral blood flow recorded from the surface of the supra-sylvian gyrus in anesthetized cats. This action reached a maximum 1-4 min after injection and continued for 10 min. However, the compound had negligible effects on other cardiorespiratory functions at the doses examined. These results suggest that the compound selectively increases cerebral blood flow. |
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| AbstractList | Dehydroevodiamine hydrochloride (0.1-0.3 mg/kg iv), which was isolated from the leaves of Evodia rutaecarpa, increased the cerebral blood flow recorded from the surface of the supra-sylvian gyrus in anesthetized cats. This action reached a maximum 1-4 min after injection and continued for 10 min. However, the compound had negligible effects on other cardiorespiratory functions at the doses examined. These results suggest that the compound selectively increases cerebral blood flow. |
| Author | Takeda, Ryuji Haji, Akira Momose, Yasunori Nakanishi, Suehiro Horiuchi, Takahiro Arisawa, Munehisa |
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| Keywords | Fissipedia Regional blood flow Carnivora Rutaceae Central nervous system Biological activity Medicinal plant Vertebrata Mammalia Folk medicine Dicotyledones Animal Angiospermae Cat Plant origin Spermatophyta Hemodynamics Brain (vertebrata) |
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| Snippet | Dehydroevodiamine hydrochloride (0.1-0.3 mg/kg iv), which was isolated from the leaves of Evodia rutaecarpa, increased the cerebral blood flow recorded from... |
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| SubjectTerms | ACIDE CHLORHYDRIQUE ACIDO CLORHIDRICO Alkaloids - isolation & purification Alkaloids - pharmacology Anesthesia Animals Biological and medical sciences BLOOD CIRCULATION BRAIN Cats CEREBRAL CORTEX CEREBRO Cerebrovascular Circulation - drug effects CHEMICAL COMPOSITION CIRCULACION SANGUINEA CIRCULATION SANGUINE COMPOSICION QUIMICA COMPOSITION CHIMIQUE DEBIT DERIVATIVES DRUG PLANTS Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - pharmacology ENCEPHALE FELIDAE Female FEUILLE FLOW RATE GASTO General pharmacology Hemodynamics - drug effects HOJAS HYDROCHLORIC ACID INDUCTION LEAVES Male Medical sciences MEDICINAL PLANTS Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments PLANTAS MEDICINALES PLANTE MEDICINALE Respiratory Function Tests RUTACEAE Tropical medicine |
| Title | Increased Feline Cerebral Blood Flow Induced by Dehydroevodiamine Hydrochloride from Evodia rutaecarpa |
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