Mechanism of Activation and Inactivation of Gq/Phospholipase C-β Signaling Nodes

Harden et al examine C-beta signaling nodes with regard to the mechanism of activation and inactivation of Gq/phospholipase.

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Bibliographic Details
Published inChemical reviews Vol. 111; no. 10; pp. 6120 - 6129
Main Authors Harden, T. Kendall, Waldo, Gary L, Hicks, Stephanie N, Sondek, John
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 12.10.2011
Subjects
Activation
Animals
Biocatalysis
Enzymes
GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry
GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism
Guanosine Triphosphate - metabolism
Hardening
Humans
Hydrolysis
Inactivation
Lipid Metabolism
Phospholipase
Phospholipase C beta - chemistry
Phospholipase C beta - metabolism
Phosphorylation
Protein Binding
Protein Conformation
Receptors, G-Protein-Coupled - metabolism
Signal Transduction
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Summary:Harden et al examine C-beta signaling nodes with regard to the mechanism of activation and inactivation of Gq/phospholipase.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-2665
1520-6890
DOI:10.1021/cr200209p