Noncoding RNA

Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as , control the expression of genes encoding virulence factors or metabolic proteins. They are extremely diverse and include noncoding RNAs (sRNA), antisense RNAs, and some 5' or 3' untranslate...

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Published inMicrobiology spectrum Vol. 7; no. 2
Main Authors Desgranges, E, Marzi, S, Moreau, K, Romby, P, Caldelari, I
Format Journal Article
LanguageEnglish
Published United States ASM Press 01.03.2019
American Society for Microbiology
Subjects
Bacterial Genetics, Cell Biology, Physiology
Biochemistry, Molecular Biology
Life Sciences
Molecular biology
RNA, Bacterial
RNA, Small Untranslated
Staphylococcus aureus
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Summary:Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as , control the expression of genes encoding virulence factors or metabolic proteins. They are extremely diverse and include noncoding RNAs (sRNA), antisense RNAs, and some 5' or 3' untranslated regions of messenger RNAs that act as sensors for metabolites, tRNAs, or environmental conditions (e.g., temperature, pH). In this review we focus on specific examples of sRNAs of that illustrate how numerous sRNAs and associated proteins are embedded in complex networks of regulation. In addition, we discuss the CRISPR-Cas systems defined as an RNA-interference-like mechanism, which also exist in staphylococcal strains.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:2165-0497
2165-0497
DOI:10.1128/microbiolspec.GPP3-0038-2018