Polymicrobial Spontaneous Pyogenic Spondylodiscitis: A Very Rare Entity

Spontaneous pyogenic spondylodiscitis (SPS) is an uncommon disease. The most common causative organism of SPS is Staphylococcus aureus, followed by Gram-negative bacilli in 4%-30% of the cases. Polymicrobial SPS is very rare, with only a few cases reported in the literature. We report a case of poly...

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Bibliographic Details
Published inJournal of Medical Sciences Vol. 42; no. 6; pp. 285 - 288
Main Authors Mangal, Vishal, Hasvi, Jayaraj, Dey, Subir, Menon, Anil Shankar
Format Journal Article
LanguageEnglish
Published 國防醫學院 01.11.2022
Medknow Publications and Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Subjects
Backache
case report
Health aspects
klebsiella oxytoca
Liver cirrhosis
mycobacterium tuberculosis spondylodiscitis
polymicrobial
proteus vulgaris
Sulbactam
case report
Klebsiella oxytoca
Mycobacterium tuberculosis spondylodiscitis
Proteus vulgaris
polymicrobial
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Summary:Spontaneous pyogenic spondylodiscitis (SPS) is an uncommon disease. The most common causative organism of SPS is Staphylococcus aureus, followed by Gram-negative bacilli in 4%-30% of the cases. Polymicrobial SPS is very rare, with only a few cases reported in the literature. We report a case of polymicrobial SPS in a 43-year-old male who was recently diagnosed with autoimmune hepatitis with cirrhosis of the liver and presented with a 1-month history of progressive low backache with radiation to both the legs. Initially, he was managed as a case of Pott's spine with antitubercular therapy on the basis of immunocompromised status with positive ascitic fluid Mycobacterium tuberculosis polymerase chain reaction. However, due to lack of clinical and radiological response after 6 weeks, he underwent computed tomography-guided biopsy of the affected region. The culture from the biopsy specimen yielded Klebsiella oxytoca and Proteus vulgaris. He was managed with culture-sensitive antimicrobials. To the best of our knowledge, this is the first case of polymicrobial SPS caused by K. oxytoca, P. vulgaris, and M. tuberculosis.
ISSN:1011-4564
DOI:10.4103/jmedsci.jmedsci_210_21