Erroneous gender identification by the amelogenin sex test

Human gender identification, based on the amelogenin gene, has important applications in forensic casework, prenatal diagnosis, DNA databasing, and blood sample storage. However, we report on the first known case, in the Israeli population, of an amelogenin sex test failure on a phenotypically norma...

Full description

Saved in:
Bibliographic Details
Published inJournal of forensic sciences Vol. 49; no. 2; p. 258
Main Authors Michael, Abebe, Brauner, Paul
Format Journal Article
LanguageEnglish
Published United States 01.03.2004
Subjects
Amelogenin
Chromosomes, Human, Y
Dental Enamel Proteins - genetics
DNA Fingerprinting - methods
Electrophoresis, Capillary
Forensic Anthropology
Humans
Karyotyping
Male
Polymerase Chain Reaction
Sex Determination Analysis
Tooth Germ
Online AccessGet more information

Cover

More Information
Summary:Human gender identification, based on the amelogenin gene, has important applications in forensic casework, prenatal diagnosis, DNA databasing, and blood sample storage. However, we report on the first known case, in the Israeli population, of an amelogenin sex test failure on a phenotypically normal male. He was typed as a female by both the AmpFlSTR SGM plus and GenePrint kits. Subsequent, karyotyping of the soldier's blood sample showed no abnormalities. These results suggest that the determination of sex, based on the amelogenin test, should be interpreted cautiously.
ISSN:0022-1198
DOI:10.1520/JFS2003223