Palladium-Catalyzed Intramolecular Hydroamination of Propargylic Carbamates and Carbamothioates

An efficient and simple methodology was developed for the synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials using Pd(OAc)2 and n-Bu4NOAc as catalysts in DCE at room temperature.

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Bibliographic Details
Published inOrganic letters Vol. 16; no. 5; pp. 1434 - 1437
Main Authors Alamsetti, Santosh Kumar, Persson, Andreas K. Å, Bäckvall, Jan-E
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 07.03.2014
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
CONVENIENT SYNTHESIS
ALCOHOLS
OXIDATIVE CARBOCYCLIZATION
4-ALKYLIDENE-2-OXAZOLIDINONES
ISOCYANATES
ARYL
OXAZOLIDINONES
ALLENYNES
ENALLENES
CYCLIZATION
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Summary:An efficient and simple methodology was developed for the synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials using Pd(OAc)2 and n-Bu4NOAc as catalysts in DCE at room temperature.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1523-7060
1523-7052
1523-7052
DOI:10.1021/ol5002279