SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants

This Viewpoint reviews circulating SARS-CoV-2 genetic variants and mechanisms of immunity by which they might escape coronavirus vaccine-induced protection and proposes 6 measures to address them, including enhanced variant isolation and testing procedures and continued adherence to mask-wearing and...

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Bibliographic Details
Published inJAMA : the journal of the American Medical Association Vol. 325; no. 9; pp. 821 - 822
Main Authors Moore, John P, Offit, Paul A
Format Journal Article
LanguageEnglish
Published United States American Medical Association 02.03.2021
Subjects
Antibodies, Monoclonal - therapeutic use
Coronaviruses
COVID-19 - prevention & control
COVID-19 - transmission
COVID-19 - virology
COVID-19 Vaccines
Genetic diversity
Genetic variance
Humans
Mutation
Public health
RNA, Messenger
SARS-CoV-2 - genetics
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Testing procedures
Vaccines
Viral diseases
Virus Shedding
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Summary:This Viewpoint reviews circulating SARS-CoV-2 genetic variants and mechanisms of immunity by which they might escape coronavirus vaccine-induced protection and proposes 6 measures to address them, including enhanced variant isolation and testing procedures and continued adherence to mask-wearing and other established public health measures.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2021.1114