Synthetic Micelle Sensitive to IR Light via a Two-Photon Process

• Published in: Journal of the American Chemical Society Vol. 127; no. 28; pp. 9952 - 9953
• Main Authors: Goodwin, Andrew P, Mynar, Justin L, Ma, Yingzhong, Fleming, Graham R, Fréchet, Jean M. J
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 20.07.2005; Amer Chemical Soc
• Subjects: Biological and medical sciences; Biological effects of radiation; Chemistry; Chemistry, Multidisciplinary; Colloidal state and disperse state; Drug Delivery Systems; Exact sciences and technology; Fundamental and applied biological sciences. Psychology; General and physical chemistry; Hydrophobic and Hydrophilic Interactions; Infrared Rays; Micelles; Micelles. Thin films; Naphthoquinones - chemistry; Non ionizing radiations. Hertzian waves. Biooptics; Oxazines - chemistry; Photons; Physical Sciences; Science & Technology; Surface-Active Agents; Tissues, organs and organisms biophysics; ACID; THERAPY; MECHANISM; DRUG-DELIVERY; PH; NILE RED; PHOTOLYSIS; COPOLYMER MICELLES; LIPOSOMES; AQUEOUS-SOLUTION; Ethylene oxide polymer; Photodynamic therapy; Photoactivation; Non ionic surfactant; Aqueous solution; Experimental study; Infrared irradiation; Micellar solution; Oxazine dye; Fluorescence spectrometry; Ultraviolet visible spectrometry
• ISSN: 0002-7863; 1520-5126
• DOI: 10.1021/ja0523035

A micellar assembly of molecules constituted of poly(ethylene glycol) as the hydrophilic component and 2-diazo-1,2-naphthoquinone as the hydrophobic component was shown to be destroyed in a two-photon photoreaction triggered by infrared light with release of an encapsulated fluorescent probe molecule.