Nickel-Catalyzed Carboxylation of Aryl and Heteroaryl Fluorosulfates Using Carbon Dioxide

• Published in: Organic letters Vol. 21; no. 7; pp. 2464 - 2467
• Main Authors: Ma, Cong, Zhao, Chuan-Qi, Xu, Xue-Tao, Li, Zhao-Ming, Wang, Xiang-Yang, Zhang, Kun, Mei, Tian-Sheng
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 05.04.2019; Amer Chemical Soc
• Subjects: aromatic hydrocarbons; carbon dioxide; carboxylation; carboxylic acids; chemical structure; Chemistry; Chemistry, Organic; phenol; Physical Sciences; Science & Technology; PALLADIUM; COMPLEX; INSERTION; C-H CARBOXYLATION; HYDROCARBONS; PHENOLS; CO2; BONDS; SELECTIVITY; BROMIDES

The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields...