Nickel-Catalyzed Carboxylation of Aryl and Heteroaryl Fluorosulfates Using Carbon Dioxide

The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields...

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Bibliographic Details
Published inOrganic letters Vol. 21; no. 7; pp. 2464 - 2467
Main Authors Ma, Cong, Zhao, Chuan-Qi, Xu, Xue-Tao, Li, Zhao-Ming, Wang, Xiang-Yang, Zhang, Kun, Mei, Tian-Sheng
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 05.04.2019
Amer Chemical Soc
Subjects
aromatic hydrocarbons
carbon dioxide
carboxylation
carboxylic acids
chemical structure
Chemistry
Chemistry, Organic
phenol
Physical Sciences
Science & Technology
PALLADIUM
COMPLEX
INSERTION
C-H CARBOXYLATION
HYDROCARBONS
PHENOLS
CO2
BONDS
SELECTIVITY
BROMIDES
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Summary:The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-7060
1523-7052
1523-7052
DOI:10.1021/acs.orglett.9b00836