Cytotoxic Constituents from Leaves of Aglaia elliptifolia
Three new cytotoxic compounds, rocagloic acid (1), elliptifoline (2), and elliptinol (3) were isolated from the leaves of Aglaia elliptifolia. The structures of compounds 1−3 were determined by spectral (NMR, MS) and chemical analysis.
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| Published in | Journal of natural products (Washington, D.C.) Vol. 64; no. 1; pp. 92 - 94 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
WASHINGTON
American Chemical Society
01.01.2001
Amer Chemical Soc American Society of Pharmacognosy |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Three new cytotoxic compounds, rocagloic acid (1), elliptifoline (2), and elliptinol (3) were isolated from the leaves of Aglaia elliptifolia. The structures of compounds 1−3 were determined by spectral (NMR, MS) and chemical analysis. |
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| AbstractList | Three new cytotoxic compounds, rocagloic acid (1), elliptifoline (2), and elliptinol (3) were isolated from the leaves of Aglaia elliptifolia. The structures of compounds 1-3 were determined by spectral (NMR, MS) and chemical analysis. Three new cytotoxic compounds, rocagloic acid (1), elliptifoline (2), and elliptinol (3) were isolated from the leaves of Aglaia elliptifolia. The structures of compounds 1−3 were determined by spectral (NMR, MS) and chemical analysis. |
| Author | Duh, Chang-Yih Wang, Shang-Kwei Cheng, Yu-Jyh |
| Author_xml | – sequence: 1 givenname: Shang-Kwei surname: Wang fullname: Wang, Shang-Kwei – sequence: 2 givenname: Yu-Jyh surname: Cheng fullname: Cheng, Yu-Jyh – sequence: 3 givenname: Chang-Yih surname: Duh fullname: Duh, Chang-Yih |
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| Cites_doi | 10.1016/S0031-9422(98)00305-7 10.1021/np50055a010 10.1016/S0031-9422(96)00763-7 |
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| Copyright | Copyright © 2001 American Chemical Society and American Society of Pharmacognosy 2001 INIST-CNRS |
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| Keywords | Antineoplastic agent Diol Pharmacognosy Cytotoxicity Plant leaf Tricyclic compound Oxygen heterocycle Meliaceae In vitro Biological activity Pyrrolidine derivatives Medicinal plant Cell line Hydroxyacid Dicotyledones Angiospermae Plant origin Carboxamide Isolation Spermatophyta Aromatic compound Structural analysis |
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| References | Dong, H (WOS:000079392800029) 1999; 50 Nugroho, BW (WOS:A1997WP71300009) 1997; 44 SAIFAH, E (WOS:A1988M256700010) 1988; 51 Duh, CY (WOS:000083978600010) 1999; 62 Cui, BL (WOS:A1997YK20800004) 1997; 53 Roux, D (WOS:000077480300043) 1998; 49 GERAN, RI (WOS:A1972O254200001) 1972; 3 DUH, CY (WOS:A1993MC47300052) 1993; 34 HOU, RS (WOS:A1995RR64900026) 1995; 58 Duh C.-Y. (np000341qb00003/np000341qb00003_1) 1993; 857 Roux D. (np000341qb00005/np000341qb00005_1) 1998; 49 Dong H. (np000341qb00006/np000341qb00006_1) 1999; 50 Hou R.-S. (np000341qb00002/np000341qb00002_1) 1995; 58 Saifah E. (np000341qb00004/np000341qb00004_1) 1988; 51 Cui B. (np000341qb00007/np000341qb00007_1) 1997; 53 Nugroho B. W. (np000341qb00009/np000341qb00009_1) 1997; 44 Geran R. I. (np000341qb00001/np000341qb00001_1) 1972; 3 Duh C.-Y. (np000341qb00010/np000341qb00010_1) 1999; 62 |
| References_xml | – volume: 49 start-page: 1745 year: 1998 ident: WOS:000077480300043 article-title: Foveolins A and B, dammarane triterpenes from Aglaia foveolata publication-title: PHYTOCHEMISTRY contributor: fullname: Roux, D – volume: 53 start-page: 17625 year: 1997 ident: WOS:A1997YK20800004 article-title: Novel cytotoxic 1H-cyclopenta[b]benzofuran lignans from Aglaia elliptica publication-title: TETRAHEDRON contributor: fullname: Cui, BL – volume: 44 start-page: 1455 year: 1997 ident: WOS:A1997WP71300009 article-title: Insecticidal rocaglamide derivatives from Aglaia duppereana publication-title: PHYTOCHEMISTRY contributor: fullname: Nugroho, BW – volume: 34 start-page: 857 year: 1993 ident: WOS:A1993MC47300052 article-title: DEHYDROODORIN, A CYTOTOXIC DIAMIDE FROM THE LEAVES OF AGLAIA-FORMOSANA publication-title: PHYTOCHEMISTRY contributor: fullname: DUH, CY – volume: 3 start-page: 1 year: 1972 ident: WOS:A1972O254200001 article-title: PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL-PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL-SYSTEMS publication-title: CANCER CHEMOTHERAPY REPORTS PART 3 contributor: fullname: GERAN, RI – volume: 58 start-page: 1126 year: 1995 ident: WOS:A1995RR64900026 article-title: SINUGIBBEROL, A NEW CYTOTOXIC CEMBRANOID DITERPENE FROM THE SOFT CORAL SINULARIA-GIBBEROSA publication-title: JOURNAL OF NATURAL PRODUCTS-LLOYDIA contributor: fullname: HOU, RS – volume: 50 start-page: 899 year: 1999 ident: WOS:000079392800029 article-title: Eicosenones and methylated flavonols from Amomum koenigii publication-title: PHYTOCHEMISTRY contributor: fullname: Dong, H – volume: 51 start-page: 80 year: 1988 ident: WOS:A1988M256700010 article-title: PIRIFERINE, A NEW PYRROLIDINE ALKALOID FROM AGLAIA-PIRIFERA LEAVES publication-title: JOURNAL OF NATURAL PRODUCTS contributor: fullname: SAIFAH, E – volume: 62 start-page: 1518 year: 1999 ident: WOS:000083978600010 article-title: Cytotoxic terpenoids from the formosan soft coral Nephthea brassica publication-title: JOURNAL OF NATURAL PRODUCTS contributor: fullname: Duh, CY – volume: 50 start-page: 902 year: 1999 ident: np000341qb00006/np000341qb00006_1 publication-title: Phytochemistry contributor: fullname: Dong H. – volume: 62 start-page: 1521 year: 1999 ident: np000341qb00010/np000341qb00010_1 publication-title: -F. J. Nat. Prod. contributor: fullname: Duh C.-Y. – volume: 49 start-page: 1748 year: 1998 ident: np000341qb00005/np000341qb00005_1 publication-title: Phytochemistry doi: 10.1016/S0031-9422(98)00305-7 contributor: fullname: Roux D. – volume: 58 start-page: 1130 year: 1995 ident: np000341qb00002/np000341qb00002_1 publication-title: J. Nat. Prod. contributor: fullname: Hou R.-S. – volume: 857 start-page: 858 year: 1993 ident: np000341qb00003/np000341qb00003_1 publication-title: Phytochemistry contributor: fullname: Duh C.-Y. – volume: 51 start-page: 82 year: 1988 ident: np000341qb00004/np000341qb00004_1 publication-title: J. Nat. Prod. doi: 10.1021/np50055a010 contributor: fullname: Saifah E. – volume: 53 start-page: 17632 year: 1997 ident: np000341qb00007/np000341qb00007_1 publication-title: Tetrahedron contributor: fullname: Cui B. – volume: 44 start-page: 1461 year: 1997 ident: np000341qb00009/np000341qb00009_1 publication-title: Phytochemistry doi: 10.1016/S0031-9422(96)00763-7 contributor: fullname: Nugroho B. W. – volume: 3 start-page: 91 year: 1972 ident: np000341qb00001/np000341qb00001_1 publication-title: J. Cancer Chemother. Rep. contributor: fullname: Geran R. I. |
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| Snippet | Three new cytotoxic compounds, rocagloic acid (1), elliptifoline (2), and elliptinol (3) were isolated from the leaves of Aglaia elliptifolia. The structures... |
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| SubjectTerms | Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Benzene Derivatives - chemistry Benzene Derivatives - pharmacology Benzofurans - chemistry Benzofurans - pharmacology Biological and medical sciences Chemistry, Medicinal China Chromatography, Thin Layer Diamide - analogs & derivatives Diamide - chemistry Diamide - pharmacology Drug Screening Assays, Antitumor General pharmacology Humans Life Sciences & Biomedicine Magnetic Resonance Spectroscopy Mass Spectrometry Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology & Pharmacy Pharmacology. Drug treatments Plant Leaves - chemistry Plant Sciences Plants, Medicinal - chemistry Pyrroles - chemistry Pyrroles - pharmacology Science & Technology Spectrophotometry, Infrared Tumor Cells, Cultured |
| Title | Cytotoxic Constituents from Leaves of Aglaia elliptifolia |
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