Cytotoxic Constituents from Leaves of Aglaia elliptifolia

• Published in: Journal of natural products (Washington, D.C.) Vol. 64; no. 1; pp. 92 - 94
• Main Authors: Wang, Shang-Kwei, Cheng, Yu-Jyh, Duh, Chang-Yih
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 01.01.2001; Amer Chemical Soc; American Society of Pharmacognosy
• Subjects: Antineoplastic Agents, Phytogenic - isolation & purification; Antineoplastic Agents, Phytogenic - pharmacology; Benzene Derivatives - chemistry; Benzene Derivatives - pharmacology; Benzofurans - chemistry; Benzofurans - pharmacology; Biological and medical sciences; Chemistry, Medicinal; China; Chromatography, Thin Layer; Diamide - analogs & derivatives; Diamide - chemistry; Diamide - pharmacology; Drug Screening Assays, Antitumor; General pharmacology; Humans; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Medical sciences; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Plant Leaves - chemistry; Plant Sciences; Plants, Medicinal - chemistry; Pyrroles - chemistry; Pyrroles - pharmacology; Science & Technology; Spectrophotometry, Infrared; Tumor Cells, Cultured; Asia; Taiwan; China; Antineoplastic agent; Diol; Pharmacognosy; Cytotoxicity; Plant leaf; Tricyclic compound; Oxygen heterocycle; Meliaceae; In vitro; Biological activity; Pyrrolidine derivatives; Medicinal plant; Cell line; Hydroxyacid; Dicotyledones; Angiospermae; Plant origin; Carboxamide; Isolation; Spermatophyta; Aromatic compound; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np000341q

Three new cytotoxic compounds, rocagloic acid (1), elliptifoline (2), and elliptinol (3) were isolated from the leaves of Aglaia elliptifolia. The structures of compounds 1−3 were determined by spectral (NMR, MS) and chemical analysis.