1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry
The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored.
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| Published in | Chemical reviews Vol. 114; no. 10; pp. 5572 - 5610 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Chemical Society
28.05.2014
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored. |
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| AbstractList | The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored. |
| Author | Li, Cui-Yun Wang, Xiao-Ming Yang, Yong-Hua Hu, Yang Zhu, Hai-Liang |
| AuthorAffiliation | State Key Laboratory of Pharmaceutical Biotechnology Nanjing University |
| AuthorAffiliation_xml | – name: Nanjing University – name: State Key Laboratory of Pharmaceutical Biotechnology |
| Author_xml | – sequence: 1 givenname: Yang surname: Hu fullname: Hu, Yang – sequence: 2 givenname: Cui-Yun surname: Li fullname: Li, Cui-Yun – sequence: 3 givenname: Xiao-Ming surname: Wang fullname: Wang, Xiao-Ming – sequence: 4 givenname: Yong-Hua surname: Yang fullname: Yang, Yong-Hua email: yangyh@nju.edu.cn – sequence: 5 givenname: Hai-Liang surname: Zhu fullname: Zhu, Hai-Liang email: zhuhl@nju.edu.cn |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24716666$$D View this record in MEDLINE/PubMed |
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| CODEN | CHREAY |
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| SubjectTerms | Agricultural chemicals Animals Anti-Infective Agents - chemical synthesis Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antiparasitic Agents - chemical synthesis Antiparasitic Agents - chemistry Antiparasitic Agents - toxicity Bacteria - drug effects Biotechnology Chemical engineering Chemical properties Chemical reactions Chemical synthesis Electrochemical Techniques Euglenozoa - drug effects Fungi - drug effects Hydrazides Hydrazines - chemistry Oxadiazoles - chemistry Solid phases Synthesis Thiadiazoles - chemical synthesis Thiadiazoles - chemistry Thiadiazoles - pharmacology |
| Title | 1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry |
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