1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored.

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Bibliographic Details
Published inChemical reviews Vol. 114; no. 10; pp. 5572 - 5610
Main Authors Hu, Yang, Li, Cui-Yun, Wang, Xiao-Ming, Yang, Yong-Hua, Zhu, Hai-Liang
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 28.05.2014
Subjects
Agricultural chemicals
Animals
Anti-Infective Agents - chemical synthesis
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
Antiparasitic Agents - chemical synthesis
Antiparasitic Agents - chemistry
Antiparasitic Agents - toxicity
Bacteria - drug effects
Biotechnology
Chemical engineering
Chemical properties
Chemical reactions
Chemical synthesis
Electrochemical Techniques
Euglenozoa - drug effects
Fungi - drug effects
Hydrazides
Hydrazines - chemistry
Oxadiazoles - chemistry
Solid phases
Synthesis
Thiadiazoles - chemical synthesis
Thiadiazoles - chemistry
Thiadiazoles - pharmacology
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Summary:The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored.
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ISSN:0009-2665
1520-6890
1520-6890
DOI:10.1021/cr400131u