Chemistry and Biochemistry of Type 2 Diabetes

Diabetes mellitus is a chronic metabolic disease resulting from insulin deficiency. Type 2 diabetes is characterized by a relative insulin deficiency, reduced insulin action, and insulin resistance of glucose transport in skeletal muscle and adipose tissue. Ross et al examine the chemistry and bioch...

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Bibliographic Details
Published inChemical reviews Vol. 104; no. 3; pp. 1255 - 1282
Main Authors Ross, Stuart A, Gulve, Eric A, Wang, Minghan
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 01.03.2004
Subjects
Animals
Biochemistry
Blood Glucose - chemistry
Blood Glucose - metabolism
Chemistry
Clinical Trials as Topic
Diabetes
Diabetes Mellitus, Type 2 - metabolism
Diabetes Mellitus, Type 2 - therapy
Disease Models, Animal
Drug Delivery Systems
Glucose
Humans
Insulin
Insulin - chemistry
Insulin - metabolism
Insulin Resistance
Signal Transduction
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Summary:Diabetes mellitus is a chronic metabolic disease resulting from insulin deficiency. Type 2 diabetes is characterized by a relative insulin deficiency, reduced insulin action, and insulin resistance of glucose transport in skeletal muscle and adipose tissue. Ross et al examine the chemistry and biochemistry of type 2 diabetes, focusing on the insulin action aspect.
Bibliography:istex:12CE2F6D142D33BD2DD59A0A663FFD30A168DCBA
ark:/67375/TPS-MKRKVTPX-0
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0009-2665
1520-6890
DOI:10.1021/cr0204653