Correlation Analysis of TEM Images of Nanocrystal Molecules

• Published in: Langmuir Vol. 24; no. 18; pp. 10084 - 10088
• Main Authors: Micheel, C. M, Zanchet, D, Alivisatos, A. Paul
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 16.09.2008
• Subjects: Chemistry; Colloidal state and disperse state; Colloids: Surfactants and Self-Assembly, Dispersions, Emulsions, Foams; COMPUTER CODES; CORRELATIONS; Dimerization; DNA; DNA - chemistry; Exact sciences and technology; General and physical chemistry; GOLD; Gold - chemistry; MATERIALS SCIENCE; Materials Testing - methods; Metal Nanoparticles; Microscopy, Electron, Transmission - methods; MOLECULES; Nanoparticles - chemistry; NANOSTRUCTURES; Nanostructures - chemistry; Nanotechnology - methods; OPTIMIZATION; Particle Size; QUANTUM DOTS; Software; Surface physical chemistry; Surface Properties; TEM Images, Nanocrystal molecules; TRANSMISSION ELECTRON MICROSCOPY; Gold; Trimer; Correlation; Quantum dot; Transition element compounds; Optimization method; Transition metal; Nanostructure; Complexes; Characterization; Transmission electron microscopy; Computer program; DNA; Imaging; Structure; Nanocrystal
• ISSN: 0743-7463; 1520-5827
• DOI: 10.1021/la801101k

Quantitative characterization of images of nanocrystals and nanostructures is a challenging but important task. The development and optimization of methods for the construction of complex nanostructures rely on imaging techniques. Computer programs were developed to quantify TEM images of nanocrystal/DNA nanostructures, and results are presented for heterodimers and trimers of gold nanocrystals. The programs presented here have also been used to analyze more complex trimers and tetramers linked by branched DNA, as well as for structures made from attaching gold nanocrystals to CdSe/ZnS core−shell quantum dots. This work has the additional goal of enabling others to quickly and easily adapt the methods for their own use.