Finding Opportunities from Surprises and Failures. Development of Rhodium-Stabilized Donor/Acceptor Carbenes and Their Application to Catalyst-Controlled C–H Functionalization
Catalyst-controlled C–H functionalization by means of the C–H insertion chemistry of rhodium carbenes has become a powerful synthetic method. The key requirements for the development of this chemistry are donor/acceptor carbenes and the chiral dirhodium tetracarboxylate catalysts. This perspective w...
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Published in | Journal of organic chemistry Vol. 84; no. 20; pp. 12722 - 12745 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
American Chemical Society
18.10.2019
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Subjects | |
Online Access | Get full text |
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Summary: | Catalyst-controlled C–H functionalization by means of the C–H insertion chemistry of rhodium carbenes has become a powerful synthetic method. The key requirements for the development of this chemistry are donor/acceptor carbenes and the chiral dirhodium tetracarboxylate catalysts. This perspective will describe the stages involved in developing this chemistry and illustrate the scope of the donor/acceptor carbene C–H functionalization. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
ISSN: | 0022-3263 1520-6904 1520-6904 |
DOI: | 10.1021/acs.joc.9b02428 |